Medication for depression is the topic????
Q.The correct medical terminology for what he calls unipolar depression is 'MAJOR depression". Stop using the idiotic term 'unipolar'. Some people have mild major depression which can often be treated in short order; the person who has it may be lucky, and they may never have another depressive episode after they are properly treated with cognitive/medicine protocol. After 4 episodes of major depression, the patient is usually treated with some antidepressant for the rest of their life. Severe major depression maybe a case that is hard to treat, and the patient is more suicidal or non-functional. If the patient suffers with general anxiety disorder (very common) along with their major depression, the pathologic condition is harder to treat. Any person suffering from any mental disease should be open to all areas of mental health, and they should not think their condition is really that much different from any other neurotransmitter abnormality. Let's talk anti depression medicines here or something closely related. People who need to shock others or discuss terrorism, holistic crap, scientology concepts, or other topics not related to depression medication should announce they will be at some Irc group or some other 'Chat' group forum meet with folks to discuss their off the wall ideas.
A.As I have clearly stated, the misnomer here applies to the naming of the groups in this hierarchy. The definition "depression and mood disorders" is not only redundant but misleading. It is, however, a permanent characteristic of the group. Only one poster insists on distinguishing between unipolar depression and any other mood disorder. My purpose in posting the prosposal, also clearly stated, was to determine whether or not there was any support for the idea of creating the group which that other poster had believed was already in existence. It will apparently not have the support required to go ahead with making a formal proposal at alt.config. Case closed. With reference to the issue of the utility of the term "unipolar depression", do a Google search using the specific phrase. You will find nearly 10,000 hits. A quick perusal of Medline reveals that your reaction is totally idiosyncratic; I cannot find so much as a case report which shows any other person reacting to those medications in this way. However, looking at the pharmacokinetics of the meds you named reveals one key point; they all rely on and affect the activity of the hepatic P450 isozyme 2D6. My guess is that you have very low 2D6 activity. The range of activity between individuals is greater than 100-fold, with the least activity most commonly found in white people of northern European descent. Your reaction to acetylsalycilate is also idiosyncratic, but again, I would look to liver enzymes for the triggering reaction. All blood flowing past the gut first passes through the liver. ASA induces some enzymes, while also permanently inhibiting others (e.g. cylco-oxygenase). Celexa uses P450 2C19, while clonazepam utilizes 3A4. Sounds like a good match up this time. I believe that if you do a websearch on "migraine diet" or "migraine trigger" you will find that certain foods are commonly associated with the induction of migraines. There is a distinction here between induced versus i diopathic migraine. The medications which affected 2D6 probably left you vulnerable to vasoactive effects of amines in foodstuffs. Clarifying the use of the term 'unipolar', I have noted you do discuss matters pertaining to depression medications. Don't get upset. When I speak of idiots and nut cases, I'm speaking of people not seeking mental illness help when they need it, people not aiding in medication problem related to depression here and the Scientologist OCD nut cases. The doctors I had seen for my migraines and worsened vasomotor rhinitis were the two supposedly best in the state I live in. They were not the only medical help I hoped would help. I saw ENT doctors, Epidemiologists, my general practitioner, and Allergy doctors. None correlated the cause of my problems. Some really thought it was chronic pain because of a record of this problem in 81 I knew it wasn't chronic pain, but I was afraid it was going to soon tun into that type of problem. It was only after I studied my migraine problem exhaustively, and only after I tried avoiding all possible common migraine/vasomotor rhinitis triggers that the answers were found. This took me over 2 years of sweat and tears. Even the psychiatrist involved in drug prescribing doubted my ideas on the cause of the migraine problem. It was only after completely weaning off all drugs and suffering the horrendous sufferings of major depression and crippling anxiety that the answers were found by me. The weaning off and on anti depressant and anti anxiety drugs for prolonged periods is true hell as you probably know. There are complex reasons for the causes of each type of mental illness and any related illness. Like soldiers in war, each patient suffering major depression experiences differing psychological and physical arduousness. None of the experts I saw properly correlated the reasons for my migraine problems. This is why each patient should always have a list of questions for their doctors, and each patient should take it upon themselves to know all they can about each medicine they take.
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